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Mortality in patients undergoing revascularization with paclitaxel eluting devices for infrainguinal peripheral artery disease: Insights from a network meta‐analysis of randomized trials

Catheterization and Cardiovascular Interventions Oct 25, 2020

Kuno T, Ueyama H, Mikami T, et al. - Using network meta‐analyses, researchers investigated if paclitaxel eluting devices enhance the risk of death in patients undergoing revascularization for infrainguinal peripheral artery disease. Searching PUBMED and EMBASE through April 2020, they identified 57 eligible randomized controlled studies including a total of 9,362 patients and comparing seven revascularization strategies (balloon angioplasty vs. bare metal stent vs. covered stent vs. paclitaxel eluting stent vs. other drug eluting stent vs. paclitaxel‐coated balloon vs. bypass surgery). Findings revealed no significant increase in mortality in correlation with using paclitaxel eluting stent, however, the long‐term mortality risk was increased in paclitaxel‐coated balloon for the treatment of infrainguinal peripheral artery disease.

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