Biris ID, Mintoft A, Harris C, et al. - Findings revealed a high in-hospital mortality in moderate to late preterm infants with congenital heart disease (CHD).

• In this single-centre retrospective case-control study for a 13-year period, a total of 247 preterm infants with CHD were matched to 494 infants without CHD.

• A significantly increased risk of in-hospital mortality was observed in CHD patients vs controls (OR 7.39).

• A higher risk of necrotising enterocolitis (OR 2.42), sepsis (OR 1.68) and invasive respiratory support ≥28 days (OR 2.34) was evident in preterm infants with CHD.

• Preterm infants with CHD had a lower risk of IVH (OR 0.22).