Hosseini Z, et al. - In this analysis of retrospectively enrolled 17 patients with relapsing-remitting MS and 18 healthy control subjects, researchers intended to use SWI and magnetization-prepared FLAIR images for sensitive differentiation of MS from benign WM lesions using the morphologic characteristics of WM lesions. They found effective assessment of central veins and hypointense rims in WM lesions was attained by the SWI/FLAIR acquisition and processing protocol. The most sensitive and specific differentiation between patients with MS and control subjects was provided by nonconfluent lesions of >3 mm with ≥1 central vein. For patients with MS and control subjects, lesion assessment took an average of 12 minutes 10 seconds and 4 minutes 33 seconds, respectively.