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Morphological characteristics of parapapillary atrophy and subsequent visual field progression in primary open-angle glaucoma

British Journal of Ophthalmology May 03, 2020

Ha A, Kim YW, Lee J, et al. - Researchers intended to determine if there is a connections between the morphological features of beta-zone parapapillary atrophy (β-zone PPA) and subsequent visual field (VF) progression in eyes with primary open-angle glaucoma (POAG). For this investigation, they involved 121 POAG eyes with β-zone PPA along with 48 normal eyes with β-zone PPA. Of the 121 POAG eyes, 49 (40.5%) exhibited VF progression during the 10.1 ± 1.9 years of follow-up. A Cox proportional hazards model showed important influences on subsequent progression from optic disc haemorrhage and higher baseline PPA irregularity index. In POAG eyes, baseline β-zone PPA margin regularity was significantly linked to subsequent VF progression. Irregular margin of β-zone PPA may be the mark of vulnerability to more glaucomatous damage in the parapapillary area.

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