Lakkis Z, et al. - Patients with rectal cancer with vs without a history of prostate cancer were compared regarding surgical outcomes. Researchers identified a total of 944 patients with rectal cancer; 10.8% of whom had a history of prostate cancer. They compared 83 patients who had received treatment for prostate cancer with 249 who had not after matching. Outcomes revealed increased short- and long-term surgical morbidity with impaired oncological outcomes in correlation to prostate cancer treatment among patients with rectal cancer. In the PC group, major surgical morbidity, anastomotic leakage, and permanent stoma, was seen more frequently. Local recurrence was significantly higher and disease-free and overall survival significantly reduced in the PC group.