Azizi AA, et al. – Here, the authors evaluate the value of 2–[¹⁸F]fluoro–2–deoxy–d–glucose ([18F]FDG)–PET imaging in detecting malignant transformation in symptomatic and asymptomatic children with plexiform neurofibroma (PN). They conclude that in asymptomatic children and adolescents, malignant transformation of PN also occurs. At early stages, detection of malignant peripheral nerve sheath tumours (MPNST) can increase the possibility of oncologically curative resections.