Fouda UM, et al. - The efficacy of vaginal misoprostol in minimizing the pain perceived by patients with no risk factors for cervical stenosis (i.e., parous women of reproductive age who have no history of cesarean section or cervical surgery) amid diagnostic office hysteroscopy is evaluated in this study. The findings suggest that the misoprostol administration prior to diagnostic office hysteroscopy seems to have no helpful role in the subgroup of patients with no risk factors for cervical stenosis.