Ois A, Vivas E, Figueras-Aguirre G, et al. - In this prospective cohort study involving 401 patients, researchers characterized variables correlated with initial misdiagnosis [defined as failure to identify correctly] of subarachnoid hemorrhage (SAH), as well as examined the association of misdiagnosis with poor outcome and complications in good Hunt and Hess (HH) cases. Data reported that misdiagnosis was confirmed in 104/401 patients who also had longer periods of hospital admission. The poor outcome has been registered in 167/401 patients. According to findings, misdiagnosis is an unresolved SAH problem, and in patients with HH 1–2 it is a missed opportunity for a good outcome. The poor outcome in misdiagnosed patients was partly explained by a higher risk of delayed cerebral ischemia and complications associated with the procedure. The diagnostic approach needs to be improved in patients who record headache only (HH 1–2) after SAH. Independent predictors of poor outcome were age, misdiagnosis, and greater clinical and radiological initial severity.