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Minimally invasive vs open pancreatectomy for right-sided and left-sided G1/G2 nonfunctioning pancreatic neuroendocrine tumors: A multicenter matched analysis with an inverse probability of treatment-weighting method

Annals of Surgical Oncology May 14, 2021

Hwang HK, Song KB, Park M, et al. - Researchers sought to compare minimally invasive surgery (MIS) and open surgery (OS) for right- or left-sided nonfunctioning pancreatic neuroendocrine tumors (NF-PNETs), focusing on surgical outcomes of both procedures. This analysis involved 859 patients: 478 OS and 381 MIS patients. For analysis, inverse probability of treatment-weighting method with propensity scores was employed. According to findings, MIS resulted in comparable short-term outcomes, vs those offered by OS, except for a longer operation time for right-sided NF-PNETs. MIS did not compromise oncologic outcomes, irrespective of tumor location or grade. Overall, MIS can be conducted safely for selected patients suffering from localized NF-PNETs.

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