dos S. Coelho F, Barros DE, Santos FA, et al. - A meta-analysis was conducted with the aim to evaluate and compare minimally invasive esophagectomy (MIE) vs open esophagectomy (OE) for treating esophageal cancer, in terms of mortality and associated complications. From MEDLINE and U.S. National Library of Medicine Clinical Trials, they included 31 articles with a total of 34,465 participants diagnosed with esophageal adenocarcinoma or squamous cell carcinoma. Findings revealed MIE to be linked with a tendency towards a decrease in 30- and 90- day mortality after surgery, as well as less frequent occurrence of major cardiovascular and respiratory complications. Also, MIE might contribute to a reduction in minor postoperative complications, to an increased necessity for a second surgical intervention, to a greater risk for vocal cord lesions; however,these results were not statistically significant. Outcomes suggest MIE as possibly more beneficial than OE, however, caution is recommended when considering these findings.