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Mild-to-moderate renal pelvis dilatation identified during pregnancy and hospital admissions in childhood: An electronic birth cohort study in Wales, UK

PLoS Medicine Aug 07, 2019

Hurt L, Wright M, Demmler J, et al. - Via a population-based cohort study that involved singleton babies born in Wales between January 1, 2009, and December 31, 2011 (n = 22,045), researchers evaluated the risk of hospital admission in children with mild-to-moderate antenatal renal pelvis dilatation (RPD) in comparison with children without such finding and investigated how the natural history of the RPD (whether the dilatation persists in later pregnancy or postpartum) or its features (unilateral vs bilateral) modified the risk of hospital admission. In children with RPD at the fetal anomaly scan (FAS) and later dilatation and in children without RPD at the FAS who had later dilatation vs children without RPD, the risk of hospital admission was greater (n = 21,057). No correlation with hospital admissions, except when the initial dilatation was bilateral could be found among children with RPD at the FAS but no dilatation in later pregnancy or postpartum. Hence, when there was persistent dilatation in later pregnancy or postpartum, children with RPD at the FAS had greater rates of hospital admissions. Moreover, to enhance the counseling of parents and develop care pathways for antenatal screening programmes, including protocols for reporting and additional investigation of RPD, these results could be utilized.
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