Grasing M, Kenned K, Sarnak MJ, et al. - This study was undertaken to investigate changes in cognition in relation to baseline eGFR in older adults participating in the Alzheimer’s Disease Neuroimaging Initiative (ADNI). Researchers conducted a longitudinal secondary analysis of an established observational cohort. Data were collected from ADNI, an NIH-funded, multicenter longitudinal observational study, which includes participants with and without cognitive impairment who were administered a comprehensive battery of neuropsychological tests every six months. The study included a total of 1,127 ADNI participants with a mean age of 74±7 years, 57% men, 97% Caucasian, and mean follow-up for 6±2.6 years. No association was found between baseline eGFR and cognitive decline in older adults with mild-moderately low eGFR in this cohort from the ADNI study.