Mild subclinical hypothyroidism is associated with paediatric dyslipidaemia
Clinical Endocrinology Jun 26, 2018
Dahl AR, et al. - In this retrospective medical record review, the researchers compared lipid profiles in children with mild subclinical hypothyroidism (SCH) with those of euthyroid children. Study participants were children (ages 2-18 years) who had undergone simultaneous measurement of TSH, free thyroxine (T4) and lipids. They compared lipids in children with mild SCH with those in euthyroid children. Results revealed that the presence of thyroid autoimmunity was not correlated with higher rates of dyslipidaemia. The findings demonstrated that mild SCH in children and adolescents was correlated with higher rates of elevated total cholesterol and elevated non-high density lipoprotein (non-HDL) cholesterol.
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