Johansson L, et al. - Experts evaluated if longstanding midlife stress was associated with cerebrospinal fluid (CSF) biomarkers of late-life Alzheimer’s disease (AD), like tau protein and amyloid beta (Aβ). As per data, unspecific neurodegenerative processes were stimulated by longstanding stress, but not the core processes of AD, at least not in the early phase of the disease. Neural degeneration may be reflected by the correlation with higher concentration of CSF t-tau. An early sign of Aβ overproduction or cerebrovascular processes in the brain may be the association with higher Aβ40.