Ishtiak-Ahmed K, et al. - Using data from 3,136 employed men and women who took part in the Danish Work Environment Cohort Study in 1990, researchers ascertained if forgetfulness in midlife indicated an increased risk of dementia in old age. Using Poisson regression analysis, incidence rate ratios (IRR) were estimated. Midlife forgetfulness was linked to a higher risk of dementia after adjusting for sociodemographic factors, comorbidities, and work-related factors. There were 749 (24%) study participants characterized as forgetful at baseline, and 86 (2.7%) were diagnosed with dementia during a total of 31,724 person-years at risk. This research is the first to explore forgetfulness and dementia in midlife, and the findings indicate that forgetfulness in midlife is an early indicator of enhanced danger of old age dementia.