von Bonsdorff MB, et al. - In this prospective cohort study, researchers analyzed physical functioning trajectories in old age in relation to cardiovascular status in midlife among white men born between 1919 and 1934 examined in the Helsinki Businessmen Study (initial n = 3,490). Considering clinical measurements carried out in 1974, three cardiovascular disease (CVD) status groups were defined: signs of CVD (diagnosed clinically or with changes in ECG, chronic disease present or used medication, n = 563); healthy and low CVD risk (n = 593) and high CVD risk (n = 1222). Of these, data on physical functioning were accessible for 1,560 men from at least one of four data collection waves between 2000-2010. “Intact,” “high stable,” “high and declining,” “intermediate and declining,” and “consistently low” functioning were the optimal number of trajectories offered by a five-class solution. Among businessmen, better development of physical functioning in old age was seen in relation to a more favorable CVD profile in midlife.