Szafarowski T, et al. - Authors evaluated microvessel density (MVD) among patients with head and neck squamous cell carcinoma (HNSCC), and assessed the predictive value of MVD in head and neck cancers. Compared to dysplasia of the upper respiratory tract epithelium, HNSCCs had statistically higher MVD values. Nonetheless, correlation of the MVD/CD34 values with local invasiveness (the T feature) of HNSCCs was not seen. Experts noted that the extent of the tumor vascularity in HNSCC could be underestimated with the assessments of MVD as performed on TMA by IHC using anti-CD34 or anti-CD105 antibodies considered to be specific for endothelial cell markers.