Zhang ML, Kem M, Rodrigues C, et al. - In order to find out the performance of AJCC 8th Edition T staging in predicting patient outcomes using a microscopic tumor size measurement method, researchers examined 106 post-neoadjuvant therapy pancreatectomies. They further assessed all individual tumor foci. They analyzed T stages based on gross size (GS) and the largest single microscopic focus size (MFS) in association with clinicopathologic variables and patient outcomes. The results indicated that higher GS- and MFS-based T stages were significantly correlated with higher tumor regression grade, lymphovascular and perineural invasion, and higher N stage. The data shhowed that, for predicting patient outcomes, MFS-based T staging is superior to GS-based T staging, implying that microscopic analyses have clinical benefit beyond the conventional use of GS measurements alone in post-neoadjuvant PDAC resections.