Yin Z, et al. - Researchers analyzed 65 pairs of cervical carcinoma tissues and matched normal tissues to determine the role of microRNA-217 (miR-217) in the growth, migration, and invasion of cervical carcinoma and as well as the role of miR-217 in the chemosensitivity of cervical carcinoma cell to cisplatin. They measured miR-217 levels using quantitative real-time-PCR assay. They used Cell Counting Kit-8, flow cytometry, wound healing, and Transwell invasion assays to determine the roles of miR-217 on the growth, apoptosis, migration, and invasion of cervical cancer SiHa and Ca-Ski cells, respectively. In vivo, the influence of miR-217 on the growth of cervical carcinoma cell was determined via the xenograft tumor model. Findings revealed a significantly lower miR-217 level in cervical carcinoma tissues vs that in noncancerous tissues. As a result of upregulation of miR-217, inhibition of the aggressiveness phenotypes of cervical carcinoma cell happened via regulation of V-Ki-Ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS). Also, upregulation of miR-217 increased the sensitivity of cervical cancer cell to cisplatin.