Zürn K, et al. - Considering that group B Streptococcus is the leading cause of meningitis and sepsis in newborns, researchers sought to analyze data on rapid and easy typing of group B Streptococcus virulence factors utilizing a genetic microarray and to relate these data to clinical manifestations. A prospective active surveillance study was carried out through two independent and nationwide reporting systems, the German Pediatric Surveillance Unit and the Laboratory Sentinel Group at Robert Koch-Institute. Between 2001 and 2003 and between 2008 and 2010, surveillance was performed. Four hundred seventy-five isolates of invasive neonatal infections were evaluated. A large collection of invasive neonatal infections showed similar distributions in molecular epidemiology, as shown in smaller cohorts earlier. The microarray used has proven to be a fast, reliable technique. The authors were able to cluster the isolates according to their virulence factors using this new tool. The clusters displayed a stronger correlation than single virulence factors with clinical data.