Qiu SQ, et al. - Researchers aimed at assessing the feasibility and accuracy of micro-computed tomography (micro-CT) as a novel method for intraoperative margin assessment in breast-conserving surgery (BCS). Using a micro-CT, they imaged lumpectomy specimens from 30 consecutive patients diagnosed with invasive breast cancer or ductal carcinoma in situ. Findings highlight that for intraoperative margin assessment in BCS, whole lumpectomy specimen micro-CT scanning is a promising technique. Hence, by providing intraoperative quick feedback on the margin status, the technique could potentially reduce the number of reoperations.