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Methotrexate for the treatment of recalcitrant erosive lichen planus of the vulva

JAMA Jan 12, 2020

Cline A, et al. - Researchers retrospectively reviewed medical records at a vulvar clinic in order to assess the effectiveness of treatment with methotrexate (MTX) in females with Erosive lichen planus of the vulva (ELPV) (characterized by desquamative, erosive dermatitis involving the vulva and vagina). Management of ELPV was defying, with topical corticosteroids, almost 25% of individuals had ELPV that was resistant to first-line therapy. Some studies of ELPV were shown that the management of recalcitrant ELPV tough. Specifically, for the treatment of recalcitrant ELPV, limited evidence was available on MTX.
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