Richards KA, et al. - In a retrospective cohort of patients with advanced PCa, researchers assessed the combination of metformin plus androgen deprivation therapy (ADT). They identified all men diagnosed with PCa between 2000-2008 that were treated with ADT with follow-up through May of 2016 using national Veterans Affairs databases. The cohort comprised of 87,344 patients, with 61% do not have diabetes mellitus (DM), 22% had DM but no metformin, and 17% had DM and were on metformin. As per findings, metformin use was noted to be associated with improved oncologic outcomes in veterans with PCa receiving ADT.