Deng X, et al. – In order to provide more data for taurine therapy, an analysis was performed to develop a reliable and simple method to identify important biological metabolites and relevant pathways for taurine in hepatic stellate cells (HSCs). The clinicians demonstared that in HSCs, there were distinct changes in biological metabolites of taurine. In mediating the mechanism of action of taurine in HSCs, three differential metabolic pathways including sphingolipid pathway, glutathione pathway, and thiamine metabolism pathway could be of key importance.