Choromańska B, et al. - For the first time, researchers determined the content of lipids (ceramide [CER], diacylglycerol [DAG], triacylglycerol, and free fatty acid [FFA]) and the expression of fatty acid translocase (FAT/CD36) and plasma membrane fatty acid-binding protein in visceral adipose tissue (VAT) and subcutaneous adipose tissue of women with morbid obesity without metabolic syndrome (MetSx-) or with metabolic syndrome (MetSx+) and compared the outcomes with those of lean controls without metabolic syndrome. By gas liquid chromatography, lipid content and fatty acid composition in each lipid subclass were estimated. In participants with obesity (MetSx-), a greater content of triacylglycerol was found in VAT. However, in relation to subcutaneous adipose tissue in MetSx+ and lean individuals, only MetSx+ subjects had increased CER content in VAT. Findings suggested an association of metabolic syndrome with the accumulation of CER in VAT, which may be related to increased FAT/CD36 protein expression.