Macedoni M, et al. - In children, adolescents and young adults with type 1 diabetes, researchers looked at the impact of metabolic control and ApoE genotypes on lipid profiles and the prevalence of dyslipidemia. Test for homoscedasticity of continuous variables was followed by ANOVA and Welch's ANOVA tests, and Chi-square test was used for categorical variables with Kruskal-Wallis test as a control. Higher mean total cholesterol, LDL-C, HDL-C, non-HDL-C, and ApoB levels were seen among women. A positive association of HbA1c levels with higher levels of LDL-C and lipoprotein(a) was apparent. Overall, more adverse lipid profiles were seen among females and subjects with suboptimal metabolic control. Independent of HbA1c, an association of ApoE4(e3/e4) alleles with significantly higher LDL-C levels was observed.