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Meta-analysis of randomized controlled trials on patent foramen ovale closure vs medical therapy for secondary prevention of cryptogenic stroke

The American Journal of Cardiology Evidence based | Mar 14, 2018

Smer A, et al. - Patent foramen ovale (PFO) closure as a strategy for secondary prevention of stroke in patients with cryptogenic stroke (CS) was assessed. PFO closure versus medical therapy was shown to be related to a significantly lower risk of recurrent stroke in patients with PFO and CS; however, closure patients more frequently develop atrial fibrillation.

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