Kiong KL, et al. - This paper incorporated the determination of the predictive accuracy of induction chemotherapy (IC) for subsequent response to chemoradiation therapy (CRT) and overall survival (OS). Poorer response to CRT could be found in patients with poor IC response and hence they ought to be directed to other modalities. Good IC response, on the other hand, did not guarantee a favorable outcome to CRT. Nonetheless, salvage therapies of curative intent ought to be offered to the patients despite treatment failure, as these patients exhibited the possibility of presenting with better prognoses.