Meta-analysis of bioprosthetic valve thrombosis after transcatheter aortic valve implantation
The American Journal of Cardiology Oct 31, 2020
Rheude T, Pellegrini C, Stortecky S, et al. - Researchers investigated the prevalence as well as the clinical effect of subclinical leaflet thrombosis (SLT) and clinical valve thrombosis (CVT) following transcatheter aortic valve implantation (TAVI), by performing this meta-analysis. They analyzed 20 studies comprising 12,128 patients. For SLT and CVT, a prevalence of 15.1% and 1.2% was estimated, respectively. Decreased left ventricular function was found to be related to elevated prevalence, while a link between oral anticoagulation and decreased prevalence of bioprosthetic valve thrombosis was also evident. Findings revealed that post-TAVI, bioprosthetic valve thrombosis was although frequently experienced but was not associated with increased mortality risk. A significantly increased risk of stroke was observed in relation to clinical valve thrombosis.
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