Meta-analysis comparing complete vs infarct related artery revascularization in patients with ST-elevation myocardial infarction and multivessel coronary disease
The American Journal of Cardiology Nov 28, 2019
Osman M, Khan SU, Farjo PD, et al. - Researchers compared complete revascularization (CR) vs infarct-related artery revascularization (IRA) for ST-elevation myocardial infarction (STEMI) management, focusing on major adverse cardiovascular events (MACE), cardiovascular mortality, all-cause mortality, stroke, repeat revascularization, myocardial infarction, and contrast induced nephropathy, via this updated meta-analysis of 10 randomized trials with 7,423 patients (CR = 3,574 and IRA = 3,849), observed over a period of 2.0 ± 0.8 years. A significant reduction in MACE was reported in relation to CR vs IRA in patients with STEMI. This decrease was derived principally by the observed low rates of repeat revascularization in the CR group.
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