Ballarini T, van Lent DM, Brunner J, et al. - Researchers examined cross-sectional data from the German DZNE-Longitudinal Cognitive Impairment and Dementia Study to ascertain if following a Mediterranean-like diet (MeDi) relates to cognitive functions and in vivo biomarkers for Alzheimer disease (AD). For this analysis, sample (n = 512, mean age 69.5 ± 5.9 years) included 169 cognitively normal participants and individuals at higher AD risk (53 with relatives with AD, 209 with subjective cognitive decline, and 81 with mild cognitive impairment). The data demonstrate the view of MeDi as a protective factor against memory decline and mediotemporal atrophy. Findings reveal that these relationships might be explained by a decrease of amyloidosis and tau pathology. There is a need for longitudinal and dietary intervention studies to analyze this conjecture and its treatment implications.