Tripathi B, Aggarwal V, Abbott JD, et al. - Researchers here utilized the National Inpatient Sample database from years 2003 to 2017 to assess contemporary trends of mechanical complications like papillary muscle rupture, ventricular septal defect/rupture, and free wall rupture in ST-elevation m'yocardial infarction (STEMI), particularly in the era of primary percutaneous coronary interventions (PPCI). They selected STEMI patients receiving PPCI, fibrinolysis alone, and fibrinolysis with subsequent PCI. Overall, they found 2,034,153 STEMI patients, among these, PPCI was received by 93.5%, and 3.2% underwent fibrinolysis alone, and 3.3% were managed with fibrinolysis with subsequent PCI. Per findings, the observed rates of overall mechanical complications post-STEMI were low even with initial use of fibrinolytics and displayed a downward temporal trend in this contemporary cohort of US patients-most of whom were treated with PPCI.