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Mean platelet volume combined red cell distribution width as biomarker of chronic obstructive pulmonary disease with pulmonary heart disease

The Clinical Respiratory Journal Sep 07, 2020

Bai Y, et al. - This study was undertaken to evaluate mean platelet volume (MPV) and red blood cell distribution width (RDW) can be biomarkers of pulmonary heart disease (PHD) occurring secondary to COPD. Researchers conducted a retrospective study including a total of 229 participants with COPD. Sixty-nine had PHD among them. They examined complete blood count, blood gas analysis, pulmonary function tests, and echocardiography. In COPD patients with PHD, both MPV and RDW‐standard deviation were significantly increased and associated with disease severity. It was shown that a combination of these two parameters presents an effective biomarker of PHD.

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