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Mean Apparent Propagator-MRI: A new diffusion model which improves temporal lobe epilepsy lateralization

European Journal of Radiology Mar 01, 2020

Ma K, Zhang X, Zhang H, et al. - In order to compare MRI volume measurements, FLAIR image intensity, Diffusion tensor imaging (DTI) and mean apparent propagator (MAP)-MRI measurements in hippocampus ipsilateral and contralateral to the epileptogenic focus for non-invasive lateralization of temporal lobe epilepsy (TLE) and also match these DTI and MAP-MRI measurements to cognitive function, researchers conducted a retrospective study to include a cohort of individuals with unilateral TLE and aged-and gendered-matched controls. A total of 23 individuals and 17 controls were examined in this study. They estimated the sensitivity, specificity, lateralization ratios and Cohen's d effect sizes of all MR measurements. In temporal lobe epilepsy, MAP-MRI measurements was found to be promising radiologic biomarkers for the non-invasive lateralization of epileptogenic foci.
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