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Maternal occupational exposure to endocrine-disrupting chemicals during pregnancy and semen parameters in adulthood: Results of a nationwide cross-sectional study among Swiss conscripts

Human Reproduction Mar 26, 2021

Istvan M, Rahban R, Dananche B, et al. - Researchers aimed at determining if maternal occupational exposure to endocrine-disrupting chemicals (EDCs) during pregnancy is associated with the semen quality of their sons. In this cross-sectional study, semen quality was evaluated among Swiss conscripts aged 18 to 22 years between 2005 and 2017. Prior to the collection of a semen sample, conscript and parent questionnaires were completed. A conscript and parent questionnaire, as well as a semen sample, were retrieved from a total of 1,737 conscripts; among these 1,045 of their mothers worked during pregnancy. Overall findings yield support for the correlation between maternal occupational exposure to potential EDCs, especially to pesticides, phthalates and heavy metals, with a reduction in several semen parameters.

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