Maternal late-pregnancy serum unmetabolized folic acid concentrations are not associated with infant allergic disease: A prospective cohort study
The Journal of Nutrition Apr 17, 2021
Best KP, Green TJ, Sulistyoningrum DC, et al. - Experts aspired to explore whether late-pregnancy serum unmetabolized folic acid (UMFA) and total folate concentrations were correlated with allergic disease risk in the offspring at 1 y of age in a population at high risk of allergy. The cohort included 561 mother-infant pairs from Western Australia. Maternal venous blood was obtained between 36 and 40 wk of gestation. Data reported that median (IQR) concentrations for UMFA and serum folate were 1.6 (0.6–4.7) and 53.2 (32.6–74.5) nmol/L, respectively. There was no correlation between maternal UMFA or serum folate concentrations measured in late pregnancy and allergic disease outcomes at 1 y of age in this cohort of children at high risk of allergic disease.
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