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Maternal hepatitis B or hepatitis C virus carrier status and long‐term infectious morbidity of the offspring: A population‐based cohort study

Journal of Viral Hepatitis May 07, 2020

Freha NA, Wainstock T, Poupko L, et al. - Researchers examined the long‐term influences of maternal hepatitis B virus (HBV) or hepatitis C virus (HCV) carrier status on the long‐term infectious morbidity of their offspring via performing a population‐based cohort study. Between the years 1991 and 2014, singleton deliveries were observed in 242,905 (99.7%) non‐carrier mothers, 591 (0.2%) HBV carriers and 186 (0.1%) HCV carriers, at a tertiary medical center. The offspring of HBV carriers vs HCV and non‐carriers had significantly higher hospitalizations related to infectious morbidity. Analyses revealed independent value of maternal HBV carrier status as risk factor for long‐term infectious morbidity of the offspring, especially for gastrointestinal and respiratory infections.

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