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Maternal cardiac function in gestational diabetes mellitus at 35–36 weeks’ gestation and after six months postpartum

Ultrasound in Obstetrics & Gynecology Jul 18, 2020

Aguilera J, Sierra AS, Azim SA, et al. - This longitudinal study was designed to compare maternal cardiac function as well as structure among women having gestational diabetes mellitus (GDM) vs those with uncomplicated pregnancy at 35‐36 weeks’ gestation and approximately six months post-delivery. This study involved 73 women experiencing GDM and 73 controls with uncomplicated pregnancies. At 35‐36 weeks’ gestation, higher E/e’ ratio and lower E/A ratio as well as global longitudinal systolic function were observed in women with GDM vs controls; no significant variations in ejection fraction and myocardial performance index were evident between the groups. In GDM women, left ventricular mass indexed for body surface area was also raised. Overall, subtle disparities in diastolic and systolic left ventricular function were evident in the third trimester in GDM patients vs controls, and although improvement post-delivery was evident but these alterations persisted for at least six months.

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