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Maternal cardiac function at 19–23 weeks’ gestation in the prediction of pre‐eclampsia

Ultrasound in Obstetrics & Gynecology Dec 13, 2020

Gibbone E, Wright A, Vallenas R, et al. - This study was sought to evaluate the factors from maternal characteristics and medical history that affect maternal cardiovascular indices, and second, to assess the potential value of maternal cardiovascular indices at 19‐23 weeks’ gestation on their own and in combination with the established biomarkers of preeclampsia (PE), including uterine artery pulsatility index, mean arterial pressure, serum placental growth factor and serum soluble fms‐like tyrosine kinase‐1, in the prediction of subsequent development of PE. Researchers conducted a prospective observational study including a total of 2,853 pregnancies. The data exhibited that the evaluation of maternal cardiovascular function gives information on the pathophysiology of PE but is not beneficial in the prognostication of PE.

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