Maternal arterial stiffness in hypertensive pregnancies with and without small‐for‐gestational‐age neonate
Ultrasound in Obstetrics & Gynecology Jun 04, 2020
Perry H, Gutierrez J, Binder J, et al. - Researchers compared maternal arterial stiffness between hypertensive pregnancies with, and those without, a small‐for‐gestational‐age (SGA) neonate and normotensive control pregnancies. They conducted a prospective cohort study including 69 patients with hypertensive disorders of pregnancy (HDP) who delivered a SGA neonate, 129 with HDP who delivered a normally grown neonate and 220 healthy controls. Observation revealed significantly higher aortic augmentation index (AIx) in pregnancies complicated by HDP with, and those without, a SGA neonate compared with uncomplicated normotensive pregnancies. Pregnancies complicated by HDP with a SGA neonate exhibited the highest aortic AIx, indicating a progression in severity of arterial stiffness abnormality with a worsening clinical picture. Findings most likely suggest systemic decreased vascular compliance and raised systemic vascular resistance in pregnancy complicated by HDP.
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