Duci M, et al. - Antenatal risk factors associated with the development of NEC were investigated. In addition, researchers examined the role of the placental alterations and the presence of prenatal signs predisposing to a severe NEC. They compared data of 136 NEC patients and 134 unaffected cases regarding antenatal findings [preeclampsia, diabetes, cholestasis, abnormal antenatal umbilical artery flow (AAUF), clinical chorioamnionitis (CC), and histology of placentas]. Findings revealed an independent predictive value of AAUF, CC, and histological chorioamnionitis (HC) for the risk of NEC. They identified more severe cases in correlation to reporting preeclampsia and HC.