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Maternal adipose tissue expansion, a missing link in the prediction of birth weight centile

Journal of Clinical Endocrinology & Metabolism Mar 05, 2020

Jarvie EM, Stewart FM, Ramsay JE, et al. - Researchers conducted the study for analyzing the contribution of maternal body fat distribution to offspring birth weight and adiposity. The sample consisted of pregnant women (n = 45) with BMI 18.0 to 46.3 kg/m2 and healthy pregnancy outcome. Maternal first trimester abdominal subcutaneous and visceral adipose tissue thickness (SAT and VAT) was evaluated through ultrasound. According to findings, VAT was the only anthropometric measure independently linked to birth weight centile. BMI was related to trimester 2 and trimesters 1 through 3 area under the curve glucose and insulin resistance (Homeostatic Model Assessment). Maternal VAT provides BMI with additional information for birth-weight prediction. VAT may be a marker for reduced SAT expansion and increased maternal fatty acid availability for placental transport.
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