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Markedly increased prevalence of migraine headaches in adolescents with bipolar disorder

Bipolar Disorders Jun 06, 2021

Mehrhof SZ, Fiksenbaum LM, Bettridge AM, et al. - In the present study, the researchers sought to examine the prevalence and correlates of migraine in a large sample of adolescents with bipolar disorder (BD). The sample consisted of 165 adolescents with BD-I, -II, or -not otherwise specified, diagnosed by the KSADS-PL semi-structured interview, and 89 healthy controls (HCs). Using the validated ID-Migraine 3-item screener, non-migraine headache and migraine headache were assessed. Migraine is much more common in adolescents with BD than in HCs; the magnitude of this association outweighs what has been reported in adult samples. Migraine correlates in youth BD are comparable to those found in adults, including a link with BD's depressive polarity.

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