Breyer MK, Ofenheimer A, Altziebler J, et al. - The present study was conducted to examine gender and gender differences in the prevalence of co-morbidities in individuals with prediabetes and diabetes and to distinguish possible risk factors correlated with prediabetes and diabetes. Researchers conducted an observational, population-based cohort study including a total of 11.014 individuals aged 6-80 years. In this study, blood samples, ankle-brachial index, ECG, dual-energy x-ray absorptiometry scan, and an interviewer-administered questionnaire were conducted. In children aged 6-10, the surprising 4.6% prevalence of prediabetes underscores the requirement for population-based studies across all ages and the onset of prevention of diabetes at a young age. The results found marked differences in co-morbidities as men with prediabetes and diabetes more usually suffer from cardiovascular disease, while women more often present arrhythmia, non-coronary artery disease, developed systemic inflammatory biomarkers and depression.