Management of suspected opioid overdose with naloxone in out-of-hospital settings: A systematic review
Annals of Internal Medicine Dec 01, 2017
Chou R, et al. - The intent of the authors was to synthesize evidence on the effects of naloxone route of administration and dosing for suspected opioid overdose in out-of-hospital settings on mortality, reversal of overdose, and harms. Additionally, they strived to prove the need for transport to a health-care facility after reversal of overdose with naloxone. The results demonstrated similar efficacy between higher-concentration intranasal naloxone (2 mg/mL) with that of intramuscular naloxone for reversal of opioid overdose. No variations were noted in the adverse events. It was also disclosed that nontransport after reversal of overdose with naloxone possibly correlated with a low rate of serious harms. However, this research did not assess the risks of transport vs nontransport.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty
-
Paid Market Research Surveys
-
Case discussions, News & Journals' summaries