Grassmann F, Yang H, Eriksson M, et al. - Mammographic features were related to cardiometabolic risk and mortality in a prospective mammographic screening cohort in Sweden (KARMA).

• A total of 57,867 women from KARMA with 49,583 sisters were included.

• Elevated risk for multiple cardiometabolic diseases was conferred by a higher number of microcalcifications, especially in women with pre-existing cardiometabolic diseases.

• Lower incidence of cardiometabolic diseases was noted in relation to dense breasts.

• A potential genetic overlap between mammographic features and cardiometabolic traits was suggested.

• Women with pre-existing cardiometabolic diseases had increased cardiometabolic mortality in relation to microcalcifications presence.

• Mammographic features together with other breast cancer risk factors could aid cardiometabolic health assessment in women attending mammographic screening.