Mizuno T, et al. - Researchers compared postoperative outcomes and overall survival between gallbladder cancer patients undergoing major hepatectomy alone or combined with pancreatoduodenectomy (HPD). From a prospectively compiled database, they identified 79 patients who underwent major hepatectomy alone and 38 patients who had HPD. Patients who underwent major hepatectomy alone for gallbladder cancer displayed favorable overall survival with low morbidity and mortality rates, whereas those who underwent HPD displayed poor overall survival and high morbidity and mortality rates. According to findings, local spreading of gallbladder cancer could be eradicated via performing HPD but may be questionable from an oncological perspective.