Chen H, Zhang TC, Yin XL, et al. - Findings demonstrate a continuous increment in the burden rate of acne vulgaris in almost all countries. It is important to understand the specific characteristics of acne vulgaris burden in order to develop more effective and targeted interventions for controlling acne burden.

• The incidence, prevalence as well as disability-adjusted life years (DALYs) on acne vulgaris were obtained in 204 countries and regions from 1990 to 2019, complying with the framework of the Global Burden of Disease 2019 Study.

• In 2019, 117.4 million incident cases of acne vulgaris, 231.2 million prevalent cases and 5.0 million DALYs were estimated worldwide, with approximately 47% increase than 1990.

• Increment in the overall age-standardized rates (ASRs) of acne vulgaris by around 0.55% annually has been noted over the past three decades.

• ASRs of acne vulgaris showed great disparities with its changing trends in gender, location, and age.

• Females had ASR around 1.3 times that of men, however, the gender disparity was narrowed for the pronounced increase among males.

• High-income regions showed higher ASRs of acne vulgaris, but the increasing trend was more prominent in other regions.