Vahidi M, Asgari S, Tohidi M, et al. - Among participants of the Tehran Lipid and Glucose Study, the link between the history of macrosomia with or without gestational diabetes mellitus (GDM) and incident maternal chronic kidney disease (CKD) was inquired herein. This analysis involved 2,669 females aged 18–50 years without known diabetes mellitus and CKD. Findings revealed a significant risk for incident maternal CKD in relation to a history of GDM/macrosomia or macrosomia alone, independent of subsequent diabetes mellitus. Pregnancy may afford a unique circumstance to detect high-risk females at risk for CKD for whom regular monitoring of renal function and provision of risk modifying strategies could be beneficial.