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Lymph node predictive model with in vitro ultrasound features for breast cancer lymph node metastasis

Ultrasound in Medicine and Biology Mar 13, 2020

Han P, Yang H, Liu M, et al. - A prospective study was conducted to examine the ultrasound features of lymph nodes observed in the bionic medium in vitro and to develop a lymph node-specific model for prediction of metastasis based on analysis of the correlation between the ultrasound features and pathology of each lymph node. Between November 1, 2017, and December 19, 2017, 373 nodes (54 patients) were included in the modeling group; from December 20, 2017, to January 12, 2018, 139 lymph nodes (22 patients) were included in the validation group. They enrolled lymph nodes from sentinel lymph node biopsy or axillary lymph node dissection. The areas under the curve of the modeling and validation groups were 0.96 and 0.93, respectively when validation was done at the patient level. The results of this study suggested that the model for prognostication of metastasis based on the ultrasound features and pathology of each lymph node is of good predictive value for lymph node metastasis.
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